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We go into what science says about the effectiveness of a B12 shot

The comparison is inherently unequal: semaglutide has decades of development, tens of thousands of patients, and proven cardiovascular benefit

Dec 1997;12(6):644-50

Such recommendations would be inconvenient for many people and could lead to some cases of acne-like symptoms in people sensitive to high doses of B12 (see Footnote B in Elevated Vitamin B12 Levels and Mortality)

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Lovell MA et al