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Clinical and safety outcomes with GLP-1 receptor agonists and SGLT2 inhibitors in type 1 diabetes: A real-world study

Chronic exposure to peroxisome proliferators in rodents leads to deposition of lipofuscin and eventually to liver tumors, most probably a consequence of oxidative stress leading to DNA damage (Evans and Lake 1998)

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Potential attenuation of chemotherapy-induced oxidative stress Supportive use to reduce neurotoxicity and hepatotoxicity Glutathione also interacts with hepatic detoxification systems

This process is called endogenous synthesis, and it primarily takes place in the liver, though almost every cell has the equipment to do it

The same effect of liraglutide was revealed in another study in patients with diabetes and hypertension but without renal impairment 27