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Anti-nausea medicines (antiemetics) may occasionally be considered, though their routine use alongside investigational medicines should always be discussed with the supervising medical team

In trials it has been administered as a weekly injection, starting with a low dose and gradually titrating upwards to minimise side effects

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5.4 Hypoglycemia Adult patients with type 2 diabetes mellitus on an insulin secretagogue (e.g., sulfonylurea) or insulin may have an increased risk of hypoglycemia with use of SAXENDA, including severe hypoglycemia

For example, GLP-1r populations in the VTA and nucleus accumbens likely allow GLP-1 to modulate salience and rewarding efficacy of drug rewards(Schmidt et al., 2016

Increased expression of Braf, Egfr, Egr1, Hdac7, Mapk1, Mapk3, Mapk14, Plcg1, Prkcg, Ptk2, Pxn, Src, Srf, and Vegfa is noted at 5 min