I dont think its mentioned in the podcast, but it has been pointed out in other articles that just like any other weight loss, theres rebound gain when people go off the drug
JAMA Neurol 76(4):420429 Brown JC, Dryburgh JR (1971) A gastric inhibitory polypeptide II: the complete amino acid sequence
7.5.1 Harmonization of global risk assessment frameworks 7.5.1.1 Standardization of exposure limits Regulatory approaches to EED exposure limits demonstrate substantial international variation
And that may be a helpful goal for people seeking treatment for AUD, said Dr
Clinical guidelines from major endocrinology organizations explicitly advise against dual GLP-1 therapy because no evidence supports added benefit and substantial evidence documents increased harm
Ive seen similar concerns in people undergoing bariatric surgery, where the focus has shifted from just losing weight to preserving muscle and monitoring for fat infiltration in the muscles, which can make you weaker, even if youre technically lighter on the scale
