The Wegovy SmPC advises that doses of insulin or sulfonylureas may need reduction when starting treatment
(PubMed) Ziegler D, Low PA, Litchy WJ, et al
Federal regulators explicitly prohibit dietary supplement companies from marketing their products with claims to diagnose, treat, or cure diseases

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Retatrutide 10mg vs 20mg vs 40mg: Which Vial Size Is Right for Your Research