In a series of acute studies using euglycemic clamps, Kim and colleagues demonstrated that a glucagon agonist IUB288 leads to improved glucose tolerance by augmenting insulin action with evidence of increased hepatic AKT phosphorylation (88)
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Abnormal mTOR activation in autism
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1 H-NMR signals corresponding to DKP were the following: 1 H-NMR (400 MHz, D 2 O) ppm: 7.18 (d, 2H, J = 8.1Hz), 6.83 (d, 2H, J = 8.1Hz), 5.19 (s, 1H, CHPh), 5.16 (d, 1H, J = 2.6Hz, H-6), 4.02 (d, 1H, J = 2.6 Hz, H-5), 3.37 (s, 1H, H-3), 1.52 (s, 3H, CH 3 ), 1.15(s, 3H, CH 3 )