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Once complexed by haem-targeting proteins or xenosiderophores, a set of TonB-dependent transporters (TBDTs) are required to transport the haem/iron into the periplasmic space, followed by transport across the inner membrane by ATP-binding cassette (ABC) transporters (Sgheiza et al., 2017)

Much of the research has focused on 3-hydroxypyrid-4-ones (Halliwell and Gutteridge, 2015)

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Upon nerve injury, SARM1 undergoes a conformational change that activates its NADase activity, leading to the rapid depletion of NAD + 232

Shanker, J.M

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