Adapt when needed: If nausea or fullness occurs, adjust portions and opt for bland, easily digestible foods until symptoms subside
21 Pharmacists should also counsel patients on the importance of maintaining adequate hydration, especially in the presence of vomiting or diarrhea, to prevent dehydration and reduce the risk of acute kidney injury
The potential nephroprotective mechanisms of GLP-1RAs likely involve GLP-1RA-mediated improvements of conventional risk factors for diabetic kidney disease (control of glycaemia, postprandial lipid level, body weight and blood pressure), but perhaps also direct effects on the kidneys
The medication may reduce appetite, improve fullness, slow gastric emptying, and support blood sugar regulation, but if calorie intake creeps back up, weight loss can stall
Severe nausea, vomiting, inability to eat, extreme fatigue, or persistent digestive distress suggest the dose may be too high
These shifts in eating patterns naturally reduce calorie intake, which contributes to gradual weight loss over time
