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& Uehara, M

10.1093/ndt/gfaa302 209 LevielF.HubnerC

You just calculate your dose based on the provided concentration

A lower lean-mass value does not automatically mean: The medication directly damaged the muscle The patient developed sarcopenia Strength declined Physical function deteriorated The patient is becoming frail The treatment caused disproportionate muscle wasting Recent methodological guidance emphasizes that body-composition terminology must be used carefully because lean tissue, fat-free mass, appendicular lean mass, and skeletal muscle refer to related but different biological compartments

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Theres a reported 40-50% reduction of opioid and alcohol intoxication in people with a history of related disorders and there are phase 2 trials showing reductions in alcohol use and opioid cravings