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Most protocols cycle on and off rather than using continuously

Signs of deficiency include: Fatigue and low energy Memory issues and brain fog Numbness or tingling in the hands and feet Mood swings or depression Pale skin and shortness of breath Supplementing Safely: Dosage and Absorption Tips While B12 is generally safe as its water-soluble (meaning excess is excreted), certain considerations can help you get the most out of your supplement: Sublingual Supplements : These are absorbed directly into the bloodstream, bypassing the digestive system, making them ideal for those with absorption issues

Froese D.S., Gravel R.A

While intravenous or intraperitoneal routes may improve bioavailability, they are difficult to apply in small animal models

Niacinamide (Vitamin B3) improves cellular energy production and supports overall metabolic functions