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MicroRNAs (miRNAs) miRNAs are short non-coding RNAs that post-transcriptionally regulate gene expression and play critical roles in testicular development, spermatogenesis, and sperm function [309]

Safety Research and Concerns Safety data comes from clinical trials, case reports, and post-marketing surveillance of related compounds: GI effects: Nausea (50-80%), the most common dose-limiting side effect Cardiovascular: Mild transient blood pressure elevations noted in Phase I studies Dermatological: Mole darkening and new nevi documented in multiple reports

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