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It increases LC3-associated phagocytosis (LAP) in macrophages via activation of the Dectin-1-Syk signaling axis and the mTOR pathway, thereby enhancing macrophage capacity to combat infection and resist sepsis progression (277)
Dual-receptor interaction By interacting with both receptor types, tirzepatide engages two pathways involved in metabolic health
The study author, Professor John Deanfield from University College London, suggested that "positive impacts on blood sugar, blood pressure, or inflammation, as well as direct effects on the heart muscle and blood vessels," may be at play