why is my weight loss so slow on semaglutide Slow Weight Loss on Semaglutide?

Despite these challenges, semaglutide has the enormous practical advantage of being an approved, regulated pharmaceutical product

doi: 10.1089/thy.2017.0428 42 LahnerEContiLCiconeFCaprielloSCazzatoMCentanniMet al

Wegovy works by binding to GLP-1 receptors in the brain that control your appetite, causing you to feel fuller and less hungry and experience less craving for food

GLP-1 drugs like Ozempic slow gastric emptying by design - in most patients this is mild and temporary, but in some it becomes severe and irreversible

At 50 pounds of loss, body composition matters enormously

CDCA and CA are transformed into secondary BAs and deconjugated by gut microbiota and can either be passively reabsorbed and reenter the circulating BA pool or excreted in feces (Thomas et al., 2008)