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El-Dirany, R., Shahrour, H., Dirany, Z., Abdel-Sater, F., Gonzalez-Gaitano, G., Brandenburg, K., et al., Biomolecules , 2021, vol

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FIGURE 1 1) The immune pathogenesis of vitiligo: (A) CD8 + T cell expression of IFN- in vitiligo lesions activated the JAK/STAT pathway after binding to IFN- receptor, thus facilitating the release of CXCL9/10

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For example, in a mouse model of inflammatory sepsis-induced acute lung injury (ALI), HSP90 inhibitors significantly reduced mortality and improved lung function, as well as local and systemic inflammation [69]