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Reactive oxygen species can oxidize and directly enhance CaMKII activity, which in turn phosphorylates and activates several Ca 2+ -handling proteins such as the cardiac ryanodine receptor RyR2 or cardiac SERCA (50)

3 Institute for Bio-Medical Convergence, College of Medicine, Catholic Kwandong University, Gangneung-si, Gangwon-do, Republic of Korea Correspondence: Jong-Hoon Kim College of Veterinary Medicine, Biosafety Research Institute, Chonbuk National University, 79 Gobong-ro, Iksan-city, Jeollabuk-Do, 54596, Republic of Korea Email [email protected] Purpose: The pathogenesis of osteoarthritis (OA) is characterized by joint degeneration

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This is critical because injured tendons, ligaments, and damaged gut mucosa have poor blood supply

chulet al (2024)

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