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Common factors include stress, changes in weight, excessive exercise, illness, travel, and hormonal imbalances such as thyroid disorders or polycystic ovary syndrome (PCOS)

doi: 10.1210/clinem/dgaa285 161 Elkind-HirschKMarrioneauxOBhushanMVernorDBhushanR

Stay hydrated Do not eat fatty and heavy foods

GIP is the main incretin hormone in healthy people, causative of most the incretin effects, but the insulin response after GIP secretion in type 2 diabetes mellitus (T2DM) is strongly reduced

Tirzepatide: available and gaining ground Tirzepatide is FDA-approved as Mounjaro (for type 2 diabetes) and Zepbound (for chronic weight management)