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M., McFarland, B

however, the ontogeny, molecular determinants, and functional consequences of this heterogeneity remain incompletely understood, particularly in psychiatric disorders, Alzheimer's disease, and amyotrophic lateral sclerosis

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In addition to biopsy and histologic study, various laboratory and clinical tests, including diascopy, radiography, and blood tests, may be necessary for the definitive diagnosis of oral pigmentations

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