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However, considering that subtle alterations in cellular conditions like ionic salt concentration, pH, ATP levels, or post-translational modifications can impact disorder-to-order transitions, the 20S substrate landscape is likely to be dynamic and contingent on the cellular state

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At the same time, these compounded medications can come with safety risks

This does not appear to be due to lack of GL displacement of the placeholder peptide P2-FV, as KIR2DS1-Fc binding dramatically reduced with GL alone, and exchange with P2-MW conferred binding to KIR2DS4-Fc

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