Sustained microglial activation leads to the release of pro-inflammatory cytokines such as TNF-, IL-1, and IL-6, which exacerbate neuronal injury and amplify amyloid and tau pathology (Kaur et al., 2019)
SURMOUNT trials Zepmound was approved based on results from phase three of the SURMOUNT-1 and SURMOUNT-2 trials
Besides microglial activation, disrupted autophagy process has been increasingly reported as a significant contributor to both chronic pain and AD (Yin et al., 2018)
doi: 10.1016/j.diabres.2024.111651
Over the past year, Novo Nordisk has introduced direct-to-consumer and cash-pay programs : Many uninsured or self-pay patients can access Ozempic or Wegovy for about $349$499 per month through manufacturer or pharmacy discount programs
Supplements like garcinia cambogia, ephedra, and bitter orange extract can introduce unnecessary risks and interfere with your medications effectiveness