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Wait 48 hours before reintroducing vitamin C in its low-pH L-ascorbic acid form, because the low pH can sting freshly treated skin

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Carries a 2021 Notice of Concern

If a patient is deficient in Folic Acid, it causes nerve damage & numbness of limbs (Peripheral Neuropathy)

Corticosteroids, methotrexate, mycophenolate, biologics (anti-TNF agents, anti-IL-6 agents, anti-CD20 agents), and JAK inhibitors each have specific mechanisms that could interact with peptide effects

However, the result is not the same for everyone, and the effect goes away when you stop the treatment