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The principal study group experienced significant decreases in both liver fat and waist circumference, roughly 20% less on average

However, from the clinical perspective, it will also be necessary to decode the mechanistic pathway for GIP that shows pharmacological activity in the brain to prevent obesity, and the regions of CNS are implicated in it

Ethics declarations Funding VSS is supported by a Department of Medicine Eliot Phillipson Clinician-Scientist Training Program, a Banting and Best Diabetes Centre Postdoctoral Fellowship at the University of Toronto and a Canadian Institutes of Health Research (CIHR) Frederick Banting and Charles Best Canada Graduate Scholarships Doctoral Research Award

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Akt activation is required at a late stage of insulin-induced GLUT4 translocation to the plasma membrane