This review aims to systematically summarize the mechanistic insights and clinical advances of GLP-1with dual or triple receptor agonists in MASLD treatment, thereby promoting a more profound comprehension and facilitating their application in clinical practice (Figure 1)
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MAPKs mediate plasma membrane bound receptor signals to activate transcription factors in the nucleus, facilitating gene expression, coordinately regulating cell proliferation, differentiation, motility, and survival (Johnson, 2011)
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Upregulation of Haploinsufficient Gene Expression in the Brain by Targeting a Long Non-coding RNA Improves Seizure Phenotype in a Model of Dravet Syndrome
BP is rich in protein, fat, and minerals (particularly Ca, Mg, Fe, and P) and gives a nutritional value to pollen similar to or greater than dry legumes and is used as a food supplement (93, 94)