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[13] Animal models [edit] Knockout mice of GPX4 die at embryonic day 8 [14] [15] and conditional inducible deletion in adult mice (neurons) results in degeneration and death in less than a month

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Uncontrolled lipid peroxidation is not only a common signal involved in the initiation or execution phases of cell death, but also plays a crucial role in crosstalk of various cell death patterns (Fig

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