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When folate receptors are blocked (e.g., by folate receptor autoantibodies ), folate cant enter the brain efficiently, leading to: Developmental delays (speech, motor skills) Regression (loss of milestones in children) Seizures, irritability, sleep disorders Psychiatric symptoms (depression, psychosis) If you suspect that you have, or a loved one has any of the symptoms mentioned in the above, then it may be a very good idea to test for folate receptor autoantibodies with the FRAT test

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