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In comparison to other hypoglycemic drugs, it was found that SGLT2 inhibitors showed a greater efficacy than DPP4 inhibitors and similar or slightly less efficacy compared to metformin and TZDs (15,141)

[5] Additionally, GLP-1 receptor agonists carry risks of gallbladder disease (cholelithiasis, cholecystitis) and pancreatitis that may present with abdominal pain and other gastrointestinal symptoms

Further studies are needed to confirm the antidiabetic activity of amlodipine in vivo

This makes them a safe choice for those seeking natural incretin activators for long-term metabolic health system support

K.WonH.et al (2019)

Infection risk: Though the benzyl alcohol preservative inhibits bacterial growth in the vial, any lapse in sterility (dirty needle, etc.) can introduce pathogens