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Patients typically notice reduced panic frequency within the first month, with complete symptom resolution by 3 months when B12 deficiency was the primary cause

Lenmeldy is the first FDA-approved gene therapy for MLD, which is caused by a deficiency of the arylsulfatase A (ARSA) enzyme, a state that leads to a buildup of fatty substances in the cells

Vitamin b12 stores in the liver typically last 3 to 5 years

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Most nausea and vomiting occur during dose increases rather than at stable doses

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