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Although these findings do not completely exclude the effect on kidney parenchymal cells or off-target effects, these results suggest that sulfasalazine prevents the formation of TLS not by attenuating tubular injury but via its inhibitory effect on of the cystine/glutamate transporter specifically expressed within TLS

10.1007/s13346-017-0398-z 54 DuarahS.DuraiR

4.3 Cerebrovascular disease models Given the established association between vascular health and cognitive function, the effects of semaglutide on stroke models are of particular significance

10.1007/s00210-024-03179-4 Naunyn Schmiedebergs Arch Pharmacol

This is largely thanks to a compound called rosmarinic acid

Further investigation is warranted to elucidate the underlying reasons for the elevated GLP-1 expression and receptor activity observed in the BLA of the saline control group following the cessation of Exendin-4 treatment