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Funding This study was granted from the Natural Science Foundation of Liaoning Province(2024-BSLH-322), Basic Research Projects for Higher Educational Institutions in Liaoning Province (JYTMS20230094), and the 345 Talent Project of Shengjing Hospital

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The hierarchy of the pre-appraised evidence pyramid was used to obtain information

Wegovy and Ozempic, which both contain semaglutide, begin at much lower dosages of 0.25 mg weekly

Reduce stress-related emotional outbursts: Gut bacteria have effects on the gut-brain-skin axis

Research shows berberine activates AMPK, a key enzyme in glucose metabolism and energy production