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In the original 2017 mouse study, FOXO4-DRI was reported as well-tolerated in vivo at the dosing used

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This review synthesizes evidence on MSCs derived from diverse sourcesincluding bone marrow, adipose tissue, umbilical cord, and menstrual bloodand evaluates their therapeutic potential

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The treatment of 100 M peroxynitrite exposure for 48 h resulted in an obvious but moderate SGN loss, as there were 59.3 3.71% SGNs left compared with the control group (Figure 2B), and it was selected as the peroxynitrite treatment condition for all subsequent experiments

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