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2D) are highly selective and generally facilitates the transport of nutrients from the blood to the brain although they can be bi-directional depending on the concentration gradient [20, 21]

Sorafenib is clinically used for the treatment of advanced cancers (such as renal cell carcinoma, hepatocellular carcinoma and thyroid cancer), and it induces ferroptosis in HT-1080 cells in a narrow concentration range [7]

It typically contains amino acids and four main nutrients: vitamin B12, methionine, inositol, and choline

doi: 10.1186/s42358-018-0042-8 49 WuCYYangHYLaiJH

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