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Diabetic wound healing studies demonstrate enhanced outcomes even under compromised metabolic conditions

Bioorg Chem

For individuals with Wilson's disease (a genetic disorder causing copper accumulation) or other copper metabolism disorders, theoretical caution is warranted, though even in these populations topical GHK-Cu is unlikely to pose significant risk given the minimal systemic absorption

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Such systems allow researchers to examine DSIP-mediated effects on hormone release, neuronal activity, and pathway-level signaling under controlled conditions