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Phase 2 detoxification is the critical step where these highly reactive intermediates are neutralized and prepared for safe excretion from the body

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International Journal of Clinical, Therapeutic, and Diagnostic Pathology, 2 , 5963

Rice D, Barone S (2000) Critical periods of vulnerability for the developing nervous system: evidence from humans and animal models

Similarly, Sesamum orientale plants, upon infection with the fungus Alternaria sesami displayed an initial increase in the activity of APX, MDHAR, and GR followed by a gradual decrease in the corresponding activities (Shereefa and Kumaraswamy, 2014)