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Though pilot human iPSC transplantation procedures have occurred 30,32 there are numerous residual trial design, manufacturing, administration, and ethical questions that will need to be addressed before larger-scale controlled trials can commence 10,13,29

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Metabolic syndrome is defined by five common health markers: waist circumference, triglycerides, HDL cholesterol, blood pressure, and fasting glucose

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116 Studies have shown that glucagon action reduces fatty acid synthesis in adipose tissue and the liver, and additionally, this hormone induces lipolysis causing fatty acids to be released into the circulation from these tissues, which then enables them to be transported to the target tissues such as skeletal muscle to be catabolised to generate ATP when required

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Available diagnostic criteria Despite its high prevalence, there are still no universally accepted clinical criteria to characterise ME/CFS, making early and accurate diagnosis difficult (52)

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