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Preclinical data have not shown prominent adverse effects, but human safety data are limited

Most reported improvements also failed to reach the threshold normally considered clinically important, even when statistical differences were detected

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It handles temperature variation well and stores easily, making it a pharmacy standard

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Early inflammation recruits dendritic cells and macrophages, which present thyroid autoantigensprimarily thyroglobulin (Tg) and thyroid peroxidase (TPO)via MHC class II molecules