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Heart Failure Possible increased risk of heart failure, particularly in patients with history of heart failure or renal impairment

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Most clinical studies measure weight changes at 24 weeks, showing that the majority of weight loss occurs within the first six months of treatment

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Rabia De Latour, a gastroenterologist and assistant professor in the Department of Medicine at the NYU Grossman School of Medicine

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PMID: 33383293

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These effects were generally dose-dependent, suggesting that starting with a lower dose could mitigate discomfort

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