retatrutide glp-1 gip glucagon triple agonist Retatrutide: How GLP-1/GIP/Glucagon Receptor Agonism Differs From Existing Compounds Cagrilintide vs Retatrutide Compared |

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Retatrutide Retatrutide ( LY-3437943 ) is an experimental drug for obesity developed by the American pharmaceutical company Eli Lilly and Company

doi: 10.1016/j.neuropharm.2021.108662 106 AlvarezEMartinezMDRonceroIChowenJAGarcia-CuarteroBGispertJDet al

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Similarly, in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced PD mouse model, GLP-1 analogues were reported to protect the brain from MPTP-induced pathological effects, such as movement disorders, increased levels of -synuclein, chronic inflammation in the brain, loss of dopaminergic neurons, oxidative stress, and expression of growth factors (65)