Several studies have indicated a role of UA in exacerbations and lung function, and in the physical capacity of patients with COPD
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(iii) The number of studies on the effects of l-Cys on human health based on clinical trials is limited and in many cases these are very preliminary studies in which the studied population does not reflect a standard population (considering aspects such as age, sex, etc.)
Clinically, melatonin has been reported to reduce the risk of hemorrhagic transformation after tissue plasminogen activator (t-PA) therapy in ischemic stroke (150, 151), suggesting a potential role in improving thrombolytic safety through modulation of BBB permeability
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