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Slower gastric emptying increases the likelihood that a large, rich, or acidic meal will sit in the stomach longer, and when that is combined with foods or behaviors that relax the lower oesophageal sphincter, reflux becomes more likely and more noticeable

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The additional GIP component amplifies the GLP-1 effects rather than simply adding to them

Rapid weight loss can leave the skin feeling loose, less dense, and "deflated." The good news is that these changes dont have to be permanent: with the right combination of daily habits and targeted clinical skincare, you can help your skin feel firmer and more resilient

What clinical trials show about semaglutide's weight loss timeline