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[DOI] [PMC free article] [PubMed] [Google Scholar] 182.Shuto Y, Shibasaki T, Otagiri A, et al

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It is frequently examined in studies focused on adipose-cell signaling, energy balance, and metabolic efficiency, where researchers investigate how modulation of NNMT activity affects cellular behavior and downstream biological responses

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NNMT catalyzes the transfer of a methyl group from S-adenosylmethionine (SAM) to nicotinamide, producing 1-methylnicotinamide (1-MNA)