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In a Mayo Clinic study presented at an annual meeting of the Endocrine Society in July 2025, researchers found that, over 18 months, 40 postmenopausal women who combined the GLP-1 drug tirzepatide (used in Mounjaro and Zepbound) with hormone therapy lost an average of 17 percent of their body weight

It turns out that Jelly Roll did use a GLP-1 but just for a bit

But while these two peptides can have similar effects, they work in slightly different ways

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These may include growth hormone-releasing peptides (GHRPs), peptide hormones, growth factors, and mimetics that are banned by anti-doping organizations

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