The Dual Agonist Breakthrough: Why Two Is Better Than One Tirzepatide, the first dual GLP-1/GIP agonist to reach market, demonstrated that activating both receptors produces superior results to activating GLP-1 alone
The third accelerator is the late-stage clinical pipeline delivering next-generation efficacy milestones
Current Market Pricing (Without Insurance) For context, currently available medications in Canada cost approximately: Wegovy (Semaglutide): $450-550 CAD per month Mounjaro/Zepbound (Tirzepatide): $400-500 CAD per month Saxenda (Liraglutide): $500-600 CAD per month Expected Retatrutide Pricing Eli Lilly typically prices competitively
This could include meeting clinical eligibility criteria, trying lower-cost or alternative interventions before coverage is approved, or requiring prior authorization
Should I take iron supplements if my period is heavier on Zepbound
Sometimes an antidepressant if indicated, chosen carefully to avoid metabolic side effects