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[2] Cell Line:PDL9 cells Concentration:25 M Incubation Time:5 days Result:Decreased the protein levels of representative senescent markers, including p16, p21, and p53

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Clinical Evidence in Humans The topical evidence base is unusually robust for a research peptide: Facial aging study (71 women, 12 weeks): A GHK-Cu facial cream documented increased skin density and thickness, reduced laxity, improved clarity, and reduced fine lines and depth of wrinkles (PMID 26236730)

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None of the three compounds are listed as scheduled controlled substances under the international drug-control conventions or under the major national scheduling systems

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doi: 10.1016/j.biopha.2023.114244 37 SakaguchiMOkagawaSOkuboYOtsukaYFukudaKIgataMet al

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OSI-906 restores the sensitivity of ovarian clear cell carcinoma to cisplatin by targeting the IGF1R/AKT pathway

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