glp-1 agonist definition Glucagon-like peptide-1 Full article: GLP-1 agonists: a

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The protein/ligand visualized 12 hydrogen bond formation with the amino acids ALA 146, ASP 156, PHE 157, SER 160, SER 162, TYR 165, GLU 177, GLN 228, ASN 229, HIS 248, VAL 292, and GLU 295

10.1016/j.mce.2021.111171 83 LiT.ZhouL.FanM.ChenZ.YanL.LuH.et al (2022)

In the context of constitutive HIF-2 stabilization 75 or a defective mitochondrial electron transport chain 76 , glutamine-derived -KG is reductively carboxylated through the consumption of NADPH by IDH2 to generate citrate

10.1038/s41392-020-00428-9 82

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