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That said, BMI should not be used as a diagnostic tool for weight loss

Concerning research gaps and opportunities, Rinaman pointed to whether perinatal development of the GLP-1/GLP-1R system may help explain individual differences in responsiveness to GLP-1R agonists, why there are sex differences in the endogenous GLP-1/GLP-1R system and why GLP-1R agonists are more effective for weight loss in women than in men, and whether chronic exposure to GLP-1R agonists affects central GLP-1 receptors

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Beverly Tchang, an endocrinologist and obesity specialist at NewYork-Presbyterian/Weill Cornell Medical Center, on Everyday Health

It is geared more toward users who are focused on sustained weight loss, rather than those looking to shed pounds for a short-term goal, such as an upcoming event

Notably, after 8 min, only the triagonist significantly increased GSIS (~twofold), with the mono-agonists having no effect (Fig