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Fourth-generation CAR structures, termed armored CARs, incorporate pro-inflammatory cytokines (e.g., IL-7, IL-12, IL-15, IL-18, IL-21), chemokines (e.g., CCL19, CCL21), or chemokine receptors
This biphasic response curve, where both microgram and nanogram doses work equally well, is unusual and mechanistically unclear
By enhancing energy metabolism, they help the body convert food into usable energy more efficiently
About this article Cite this article Tang, J.J., Podratz, J.L., Lange, M
Abbreviations: Akt protein kinase B, CFR, coronary flow reserve
Bonuses should feel like tools, not traps
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