7,8 Alterations in DNA damage-response pathways have been further associated with immune deficiency, infertility, premature aging and the development of atherosclerosis
If you are already taking a GLP-1 medication, read our article on important Tips for Success While Taking Weight Loss Meds
Differentiating between these entities may have important implications for treatment strategy
Common side effects are rare but may include: Mild gastrointestinal symptoms such as nausea or diarrhoea (though less common with sublingual than oral routes) Headache or dizziness in some users Skin reactions, including itching or rash, particularly in individuals sensitive to cobalt (a component of cobalamin) Unlike some other B vitamins, oral B12 supplements rarely affect urine colour
The main practical disadvantages are: poor absorption in standard capsule form, the need for consistent daily use over 8-12+ weeks before visible results, relatively higher cost for well-absorbed formats, mild and uncommon side effects like digestive discomfort or headache in some users, and the risk of unrealistic expectations from aggressive marketing claims
Key takeaways: GLP-1 agonist medications can cause many side effects