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Furthermore, mRNA and protein expression of CCL11 were both downregulated after GSDMD knockdown in THP-1 cells, suggesting that the absence of GSDMD not only reduced the release of CCL11 through pyroptosis process but also directly inhibited the CCL11 production

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Yamamoto T, Nakade Y, Yamauchi T, Kobayashi Y, Ishii N, Ohashi T, et al

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In addition to the salutary effect on the lower doses of neuroleptics, an even stronger beneficial anticataleptic effect of NaBPC157 appears with a higher dosage of both neuroleptics observed with both g and ng doses of NaBPC157

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