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In two small trials ( n = 20 and n = 32), 1500 mg/day of metformin for 3 months improved BMI, testosterone, leptin, and lipids, but had no effects on androgens, insulin resistance, or ovulation or pregnancy rates compared with placebo

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They might even trigger hypoglycemiaa potentially life-threatening condition where blood sugar drops too low

Bottom line: Supporting glutathione is a multi-step process that involves eating the molecule itself (via fruits), providing building blocks (via sulfur), and ensuring you have "recycling" agents (via Vitamin C)

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