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Explored as a possible aid for recovery and lean-mass preservation in frail or catabolic populations, though a Merck-sponsored Phase 2b trial in elderly hip-fracture patients (Adunsky et al., 2011, Archives of Gerontology and Geriatrics, PMID 21067829) was halted early over a cardiac safety signal rather than demonstrating a clear functional benefit

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The emerging research on MOTS-c as another mitochondrial peptide adds additional options for researchers designing energy-focused stacking protocols

The primary downstream effect is AMPK activation, which signals cells to shift from glucose storage to fat oxidation

There is no after-taste and for best results, it is suggested to use regularly for at least 3-4 months

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