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This test evaluates spontaneous alternation behavior, an inherent tendency in rodents to explore a new arm rather than returning to a previously visited one (Kraeuter et al., 2019)

NRF2 reprograms cellular metabolism to funnel metabolic intermediates into antioxidant pathways While NRF2 regulates the expression of antioxidant and NADPH-generating enzymes, metabolic intermediates are required to support these pathways

Cellular GSH is found mostly in the cytosol, with the remainder spread across organelles (44)

[PubMed: 4137321] 7

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